Minions Stuart, Kevin, and Bob are recruited by Scarlet Overkill, a supervillain who, alongside her inventor husband Herb, hatches a plot to take over the world.
When a new criminal comes to town, the Anti-Villain League decides to hire Gru in order to fight him off. While Gru initially refuses, he eventually agrees after his aide goes back to his evil ways.
Mumble's son, Erik, is struggling to realize his talents in the Emperor Penguin world. Meanwhile, Mumble and his family and friends discover a new threat their home -- one that will take everyone working together to save them.